{"id":4036,"date":"2019-10-03T13:10:06","date_gmt":"2019-10-03T05:10:06","guid":{"rendered":"https:\/\/www.antiaging.com.hk\/?page_id=4036"},"modified":"2023-10-08T14:15:33","modified_gmt":"2023-10-08T06:15:33","slug":"clinical-study","status":"publish","type":"page","link":"https:\/\/www.antiaging.com.hk\/en\/clinical-study\/","title":{"rendered":"Clinical Studies"},"content":{"rendered":"<div id=\"pl-4036\"  class=\"panel-layout\" ><div id=\"pg-4036-0\"  class=\"panel-grid panel-has-style\" ><div class=\"panel-row-style panel-row-style-for-4036-0\" ><div id=\"pgc-4036-0-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-4036-0-1\"  class=\"panel-grid-cell panel-grid-cell-mobile-last\" ><div id=\"panel-4036-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><strong><span style=\"font-size: 16pt; color: #008000; font-family: \u5fae\u8edf\u6b63\u9ed1\u9ad4, sans-serif;\">\u6709\u95dcNMN\u7684\u4eba\u985e\/\u53ca\u52d5\u7269\u4e4b\u81e8\u5e8a\u5be6\u9a57<\/span><\/strong><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/www.journalofsurgicalresearch.com\/article\/S0022-4804(22)00614-X\/fulltext\" target=\"_blank\" rel=\"noopener\">2023\u5e743\u6708 Nicotinamide Mononucleotide Attenuates LPS-Induced Acute Lung Injury With Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajpcell.00459.2022?rfr_dat=cr_pub++0pubmed&amp;url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org\" target=\"_blank\" rel=\"noopener\">2023\u5e743\u6708 The cardioprotective role of sirtuins is mediated in part by regulating KATP channel surface expression<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/10.1111\/bph.15980\" target=\"_blank\" rel=\"noopener\">2023\u5e743\u6708 Gut microbiota-derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s00210-023-02383-y\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 The additive effects of nicotinamide mononucleotide and melatonin on mitochondrial biogenesis and fission\/fusion, autophagy, and microRNA-499 in the aged rat heart with reperfusion injury<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/academic.oup.com\/biomedgerontology\/article-abstract\/78\/2\/186\/6678612?redirectedFrom=fulltext&amp;login=false\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 Nicotinamide Mononucleotide Alleviates Osteoblast Senescence Induction and Promotes Bone Healing in Osteoporotic Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9935856\/pdf\/41598_2023_Article_29787.pdf\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-08189-0\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 Melatonin\/nicotinamide mononucleotide\/ubiquinol: a cocktail providing superior cardioprotection against ischemia\/reperfusion injury in a common co-morbidities modelled rat<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/10.1002\/iub.2707\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/cpr.13419\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 Nicotinamide mononucleotide restores oxidative stress-related apoptosis of oocyte exposed to benzyl butyl phthalate in mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s12035-023-03251-9\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9735188\/pdf\/11357_2022_Article_705.pdf\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 The efficacy and safety of \u03b2-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #965230;\"><a style=\"color: #965230;\" href=\"https:\/\/academic.oup.com\/jcem\/advance-article-abstract\/doi\/10.1210\/clinem\/dgad027\/7027634?redirectedFrom=fulltext&amp;login=false#no-access-message\" target=\"_blank\" rel=\"noopener\">2023\u5e742\u6708 Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/www.medsci.org\/v20p0307.pdf\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Nicotinamide mononucleotides alleviated neurological impairment via anti-neuroinflammation in traumatic brain injury<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2023.1099134\/pdf\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Nicotinamide mononucleotide attenuates HIF-1\u03b1 activation and fibrosis in hypoxic adipose tissue via NAD+\/SIRT1 axis<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/advs.202207170\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Nicotinamide Mononucleotide Ameliorates Sleep Deprivation-Induced Gut Microbiota Dysbiosis and Restores Colonization Resistance against Intestinal Infections<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9876928\/pdf\/41514_2023_Article_98.pdf\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Quantification of localized NAD+ changes reveals unique specificity of NAD+ regulation in the hypothalamus<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/www.mdpi.com\/2072-6643\/15\/2\/445\/pdf?version=1674041856\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12015-022-10499-6.pdf?pdf=button\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Extracellular Vesicles from NMN Preconditioned Mesenchymal Stem Cells Ameliorated Myocardial Infarction via miR-210-3p Promoted Angiogenesis<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/journals.lww.com\/cardiovascularpharm\/Abstract\/9900\/Nicotinamide_mononucleotide_alleviates_angiotensin.144.aspx\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Nicotinamide mononucleotide alleviates angiotensin II-induced human aortic smooth muscle cell senescence in a microphysiological model<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s40266-022-00989-0\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #333399;\"><a style=\"color: #333399;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ggi.14513\" target=\"_blank\" rel=\"noopener\">2023\u5e741\u6708 Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo-controlled, double-blind study<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9823503\/pdf\/nutrients-15-00143.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7412\u6708 Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9818647\/pdf\/cells-12-00108.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7412\u6708 Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9837732\/pdf\/bpl-8-bpl220143.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7412\u6708 Nicotinamide Mononucleotide Prevents Cisplatin-Induced Mitochondrial Defects in Cortical Neurons Derived from Human Induced Pluripotent Stem Cells<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2022.971932\/pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7412\u6708 Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/24\/16053\/pdf?version=1671620946\" target=\"_blank\" rel=\"noopener\">2022\u5e7412\u6708 Mitochondrial Dysfunction and Therapeutic Perspectives in Cardiovascular Diseases<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9741512\/pdf\/ACEL-21-e13729.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7412\u6708 DNA damage contributes to age-associated differences in SARS-CoV-2 infection<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9738479\/pdf\/ijms-23-14739.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7411\u6708 Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD+\/Sirt3 Pathway in Mesenchymal Stem Cells<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9741448\/pdf\/ijms-23-14711.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7411\u6708 Nicotinamide Mononucleotide Protects against Retinal Dysfunction in a Murine Model of Carotid Artery Occlusion<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9628229\/pdf\/CPR-55-e13303.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7411\u6708 Administration of nicotinamide mononucleotide improves oocyte quality of obese mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/09553002.2023.2145029?journalCode=irab20\" target=\"_blank\" rel=\"noopener\">2022\u5e7411\u6708 NMN alleviates radiation-induced intestinal fibrosis by modulating gut microbiota<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #444452;\"><a style=\"color: #444452;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0891584922008978?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2022\u5e7411\u6708 NMN ameliorated radiation induced damage in NRF2-deficient cell and mice via regulating SIRT6 and SIRT7<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9490589\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e7411\u6708 Declining muscle NAD+ in a hyperandrogenism PCOS mouse model: Possible role in metabolic dysregulation<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/jddonline.com\/articles\/a-narrative-review-of-nicotinamide-adenine-dinucleotide-nad-intermediates-nicotinamide-riboside-and-nicotinamide-mononucleotide-for-keratinocyte-carcinoma-risk-reduction-S1545961622P1129X\/\" target=\"_blank\" rel=\"noopener\">2022\u5e7410\u6708 A Narrative Review of Nicotinamide Adenine Dinucleotide (NAD)+ Intermediates Nicotinamide Riboside and Nicotinamide Mononucleotide for Keratinocyte Carcinoma Risk Reduction<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07459-1\" target=\"_blank\" rel=\"noopener\">2022\u5e7410\u6708 The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/19\/11228\/htm\" target=\"_blank\" rel=\"noopener\">2022\u5e749\u6708 Nicotinamide Mononucleotide Prevents Retinal Dysfunction in a Mouse Model of Retinal Ischemia\/Reperfusion Injury<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9534732\/pdf\/cureus-0014-00000028812.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e749\u6708 Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9464647\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e749\u6708 Treatment of inflammatory bowel disease: Potential effect of NMN on intestinal barrier and gut microbiota<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9436820\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e749\u6708 Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers during Aging and Upon the Treatment of Nicotinamide Mononucleotide<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #008000;\"><a style=\"color: #008000;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9617129\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e749\u6708 LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9400576\/pdf\/41598_2022_Article_18272.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e748\u6708 Safety evaluation of \u03b2-nicotinamide mononucleotide oral administration in healthy adult men and women<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/academic.oup.com\/biomedgerontology\/advance-article-abstract\/doi\/10.1093\/gerona\/glac175\/6678612?redirectedFrom=fulltext\" target=\"_blank\" rel=\"noopener\">2022\u5e748\u6708 Nicotinamide mononucleotide alleviates osteoblast senescence induction and promotes bone healing in osteoporotic mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.nature.com\/articles\/s41598-022-18147-2.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e748\u6708 Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN\/NAD consumers mediated by Twist2<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.mdpi.com\/2072-6643\/14\/15\/3231\/pdf?version=1659929819\" target=\"_blank\" rel=\"noopener\">2022\u5e748\u6708 Supplementation with NAD + and Its Precursors to Prevent Cognitive Decline across Disease Contexts<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/academic.oup.com\/jmcb\/article-pdf\/14\/4\/mjac025\/45214832\/mjac025.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e748\u6708 Supplementation of nicotinamide mononucleotide improves the quality of postovulatory aged porcine oocytes<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S156757692200296X?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2022\u5e748\u6708 Nicotinamide mononucleotide ameliorates DNFB-induced atopic dermatitis-like symptoms in mice by blocking activation of ROS-mediated JAK2\/STAT5 signaling pathway<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.sciengine.com\/ABBS\/doi\/10.3724\/abbs.2022099;JSESSIONID=a218d5b0-a6fd-4ef7-8f89-a3942c6fd2b8\" target=\"_blank\" rel=\"noopener\">2022\u5e747\u6708 Nicotinamide mononucleotide improves spermatogenic function in streptozotocin-induced diabetic mice via modulating the glycolysis pathway<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/downloads.hindawi.com\/journals\/omcl\/2022\/5961123.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e747\u6708 Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07390-5\" target=\"_blank\" rel=\"noopener\">2022\u5e747\u6708 Combination of nicotinamide mononucleotide and troxerutin induces full protection against doxorubicin-induced cardiotoxicity by modulating mitochondrial biogenesis and inflammatory response<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/cpr.13303\" target=\"_blank\" rel=\"noopener\">2022\u5e747\u6708 Administration of nicotinamide mononucleotide improves oocyte quality of obese mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #000080;\"><a style=\"color: #000080;\" href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/14\/7539\/pdf?version=1657249663\" target=\"_blank\" rel=\"noopener\">2022\u5e747\u6708 Nicotinamide Mononucleotide and Coenzyme Q10 Protects Fibroblast Senescence Induced by Particulate Matter Preconditioned Mast Cells<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.mdpi.com\/2227-9059\/10\/7\/1544\/pdf?version=1656553273\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Unique Deep Radiomic Signature Shows NMN Treatment Reverses Morphology of Oocytes from Aged Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmolb.2022.895028\/pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2022.903565\/pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Metformin, Rapamycin, or Nicotinamide Mononucleotide Pretreatment Attenuate Cognitive Impairment After Cerebral Hypoperfusion by Inhibiting Microglial Phagocytosis<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9213586\/pdf\/11357_2022_Article_564.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/jasbsci.biomedcentral.com\/track\/pdf\/10.1186\/s40104-022-00716-0.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Nicotinamide mononucleotide supplementation improves the quality of porcine oocytes under heat stress<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jproteome.2c00167\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Nicotinamide Mononucleotide Administration Restores Redox Homeostasis via the Sirt3-Nrf2 Axis and Protects Aged Mice from Oxidative Stress-Induced Liver Injury<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2022\/FO\/D2FO00525E\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.jdsjournal.com\/article\/S0923-1811(22)00122-0\/fulltext\" target=\"_blank\" rel=\"noopener\">2022\u5e746\u6708 Nicotinamide mononucleotide reduces melanin production in aged melanocytes by inhibiting cAMP\/Wnt signaling<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0378111922001676?via%3Dihub\" rel=\"noopener\">2022\u5e745\u6708 The combination of nicotinamide mononucleotide and lycopene prevents cognitive impairment and attenuates oxidative damage in D-galactose induced aging models via Keap1-Nrf2 signaling<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.mdpi.com\/2073-4409\/11\/10\/1654\/pdf?version=1652707485\" rel=\"noopener\">2022\u5e745\u6708 Nicotinamide Mononucleotide Administration Amends Protein Acetylome of Aged Mouse Liver<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.eurekaselect.com\/article\/123721\" rel=\"noopener\">2022\u5e745\u6708 Distribution of Nicotinamide Mononucleotide After Intravenous Injection in Normal and Ischemic Stroke Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/15353702221094235?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" rel=\"noopener\">2022\u5e745\u6708 Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPR mt<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9158788\/pdf\/41514_2022_Article_84.pdf\" rel=\"noopener\">2022\u5e745\u6708 Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men<\/a><\/span><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-4036-0-1-1\" class=\"so-panel widget widget_sow-editor\" data-index=\"1\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0378111922001676?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2022\u5e745\u6708 The combination of nicotinamide mononucleotide and lycopene prevents cognitive impairment and attenuates oxidative damage in D-galactose induced aging models via Keap1-Nrf2 signaling<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/9\/4887\/pdf?version=1651144762\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 NAD + Precursors Repair Mitochondrial Function in Diabetes and Prevent Experimental Diabetic Neuropathy<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.thno.org\/v12p3316.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 NAD +-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/reader.elsevier.com\/reader\/sd\/pii\/S2452302X21004289?token=1641058BE33C50790693EAC282D7228F8948369BA7976A5E21DD7A454193F6DB0615C74F009DAAB017FF1927CE236C08&amp;originRegion=us-east-1&amp;originCreation=20220622063032\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.nature.com\/articles\/s41421-022-00409-y.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Treatment of SARS-CoV-2-induced pneumonia with NAD + and NMN in two mouse models<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2022.868640\/pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11033-022-07459-1\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.mdpi.com\/1422-0067\/23\/7\/3458\/pdf?version=1648103837\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 NAD + Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/reader.elsevier.com\/reader\/sd\/pii\/S0147651322002810?token=560858446389E5899B6861581084DB5A59B8550C8005D9DDD1AA82BC08D8C288E4F983BF1DFFA22D2D74905958E47D7D&amp;originRegion=us-east-1&amp;originCreation=20220625060108\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10522-022-09957-y.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/jcmm.17222\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 NAD+ ameliorates endotoxin-induced acute kidney injury in a sirtuin1\u2013dependent manner via GSK-3\u03b2\/Nrf2 signalling pathway<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11357-022-00564-w\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/academic.oup.com\/endo\/article-abstract\/163\/4\/bqac023\/6537596?redirectedFrom=fulltext&amp;login=false\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 Intestinal Epithelial NAD+ Biosynthesis Regulates GLP-1 Production and Postprandial Glucose Metabolism in Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/reader.elsevier.com\/reader\/sd\/pii\/S221323172200009X?token=D5DB8E56CDC6B8D935A5FBB08271F7353E30F8CE9AB4C7607475D41FFE0D3AB0DDF46EB6367FC16F3646839F4EEED311&amp;originRegion=us-east-1&amp;originCreation=20220625063120\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1388198121002225?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2022\u5e744\u6708 NAD supplementation improves mitochondrial performance of cardiolipin mutants<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8922828\/pdf\/12891_2022_Article_5205.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e743\u6708 Antioxidant effect of nicotinamide mononucleotide in tendinopathy<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8907257\/pdf\/41467_2022_Article_28844.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e743\u6708 Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8917163\/pdf\/41598_2022_Article_8068.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e743\u6708 Mitochondrial dysregulation occurs early in ALS motor cortex with TDP-43 pathology and suggests maintaining NAD+ balance as a therapeutic strategy<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0753332222000476?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2022\u5e743\u6708 Nicotinamide mononucleotide increases cell viability and restores tight junctions in high-glucose-treated human corneal epithelial cells via the SIRT1\/Nrf2\/HO-1 pathway<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.mdpi.com\/2072-6643\/14\/4\/755\/pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e742\u6708 Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8858315\/pdf\/41419_2022_Article_4613.pdf\" target=\"_blank\" rel=\"noopener\">2022\u5e742\u6708 PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0305417922000158?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2022\u5e741\u6708 Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #1f612e;\"><a style=\"color: #1f612e;\" href=\"https:\/\/reader.elsevier.com\/reader\/sd\/pii\/S0925443921002209?token=34E3C70E67EECE0A1F51EE2506714C0CF85593359F6CF3307C37BA2516CA0F310D3D471E1677A9F845B074628B40A477&amp;originRegion=us-east-1&amp;originCreation=20220120064531\" target=\"_blank\" rel=\"noopener\">2022\u5e741\u6708 NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury<\/a><\/span><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-4036-0-1-2\" class=\"so-panel widget widget_sow-editor\" data-index=\"2\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1440-1681.13616\" target=\"_blank\" rel=\"noopener\">2021\u5e7412\u6708 Pretreatment with Nicotinamide Mononucleotide Increases the Effect of Ischemic-Postconditioning on Cardioprotection and Mitochondrial Function Following ex vivo Myocardial Reperfusion Injury in Aged Rats<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S000398612100299X?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2021\u5e7411\u6708 Nicotinamide mononucleotide attenuates doxorubicin-induced cardiotoxicity by reducing oxidative stress, inflammation and apoptosis in rats<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8667784\/pdf\/fnut-08-756243.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e7411\u6708 The Impacts of Short-Term NMN Supplementation on Serum Metabolism, Fecal Microbiota, and Telomere Length in Pre-Aging Phase<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.121.056589?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" target=\"_blank\" rel=\"noopener\">2021\u5e7411\u6708 NAD + Metabolism in Cardiac Health, Aging, and Disease<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0955286321003314?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2021\u5e7411\u6708 Long-term treatment of Nicotinamide mononucleotide improved age-related diminished ovary reserve through enhancing the mitophagy level of granulosa cells in mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8504657\/pdf\/jir-14-5165.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e7410\u6708 \u03b2-Nicotinamide Mononucleotide (NMN) Administrated by Intraperitoneal Injection Mediates Protection Against UVB-Induced Skin Damage in Mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1471489221001272?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2021\u5e7410\u6708 Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8358781\/pdf\/fnut-08-714604.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e747\u6708 NMN Maintains Intestinal Homeostasis by Regulating the Gut Microbiota<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8277702\/pdf\/nihms-1690093.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e747\u6708 Nicotinamide Mononucleotide Prevents Cisplatin-Induced Cognitive Impairments<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8265078\/pdf\/12970_2021_Article_442.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e747\u6708 Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8256368\/pdf\/JCMM-25-5884.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e746\u6708 The new insight into extracellular NAD + degradation-the contribution of CD38 and CD73 in calcific aortic valve disease<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/jasn.asnjournals.org\/content\/32\/6\/1355?with-ds=yes\" target=\"_blank\" rel=\"noopener\">2021\u5e746\u6708 Pre-emptive Short-term Nicotinamide Mononucleotide Treatment in a Mouse Model of Diabetic Nephropathy<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8550608\/pdf\/nihms-1747752.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e746\u6708 Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0024320521002848?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2021\u5e746\u6708 Nicotinamide mononucleotide attenuates isoproterenol-induced cardiac fibrosis by regulating oxidative stress and Smad3 acetylation<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.jstage.jst.go.jp\/article\/biomedres\/42\/5\/42_173\/_pdf\/-char\/en\" target=\"_blank\" rel=\"noopener\">2021\u5e746\u6708 Nicotinamide mononucleotide augments the cytotoxic activity of natural killer cells in young and elderly mice<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8491199\/pdf\/MCO2-2-279.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e745\u6708 Nicotinamide mononucleotide ameliorates senescence in alveolar epithelial cells<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s11033-021-06351-8\" target=\"_blank\" rel=\"noopener\">2021\u5e744\u6708 Nicotinamide mononucleotide and melatonin counteract myocardial ischemia-reperfusion injury by activating SIRT3\/FOXO1 and reducing apoptosis in aged male rats<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8027253\/pdf\/fphar-12-643089.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e743\u6708 Nicotinamide Mononucleotide Combined With Lactobacillus fermentum TKSN041 Reduces the Photoaging Damage in Murine Skin by Activating AMPK Signaling Pathway<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8021789\/pdf\/fphys-12-649547.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e743\u6708 Nicotinamide Mononucleotide Attenuates Renal Interstitial Fibrosis After AKI by Suppressing Tubular DNA Damage and Senescence<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2021.628580\/pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e742\u6708 Nicotinamide Mononucleotide Restores the Meiotic Competency of Porcine Oocytes Exposed to Ethylene Glycol Butyl Ether<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.dovepress.com\/getfile.php?fileID=67017\" target=\"_blank\" rel=\"noopener\">2021\u5e742\u6708 Nicotinamide Mononucleotide Alleviates Hyperosmolarity-Induced IL-17a Secretion and Macrophage Activation in Corneal Epithelial Cells\/Macrophage Co-Culture System<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7829339\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2021\u5e741\u6708 Generation and assessment of high-quality mouse oocytes and embryos following nicotinamide mononucleotide administration<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #bf7543;\"><a style=\"color: #bf7543;\" href=\"https:\/\/pdf.sciencedirectassets.com\/271331\/1-s2.0-S0891584920X00165\/1-s2.0-S0891584920316269\/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEFQaCXVzLWVhc3QtMSJHMEUCIFwneHYwd0GV%2B9xWM%2BkttK%2Ft7meCxqj6RH2v4ilzIL17AiEA8UrNJB5zIiU5v50GXUM%2BPPaxYzq9b8%2BeBpCE9MKU76gqgwQI%2Ff%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARAEGgwwNTkwMDM1NDY4NjUiDIE3WsIa7eKKesezdSrXAwTThZoSCmfKm0FIQJWLJ4rKuoP6HXUd8M5IfLVZPBmG1S5qDCWCs6I9ZMFnO8KQp6zLryrRHXsJQ1epGnN2kpDrJOPkgwC18zw5OuehlZTvwo2UhfN0kTRlclBQUXyJIb%2FgEOgjfEk6hrDz4uLt0o0SCUMjAHZg%2F4J6qkkwiAXp7Vn%2BWgK0Y6q8i%2F5SQzRaVD%2Blvt0cKTCbHqmhhvG3%2BGH73xJ98npqHnosMFV9TcdfjZY76Yivu7aKNjEhuh9CrHN5hj73XCc4RBT6by7GC9X4JrQRlnlnSIzHgFfJa8BXeDitOmZ8pQxy9vaU0jBKSohIVt%2BaBNV9oHwsXqiBfaSOuJ07aIiVDKuX9FWYHQT2oPFEZRCMGuVhp4QIPNvHXAqHWC1lTj1uFdFw3PvXAy%2Fzw%2FAf6%2B7yGLddllhDg71CFo3AVBLZxE14iVGByYOF%2BLb9WcAGktNGw5prs6p2uIMdFtfdd72qjO9wl2sYvrOSsNE%2B3BCw4v1FbbBmV85agmDJXQ9GQvMNSBbOihd7vHsD8UFJQGbGCQw3t01rH31wNRptCKmzJ3W5PJatr1wvTCKEq%2B%2BiBFreUuTvUcSqOUIgYSqa%2BW0Cw55e0u31a2CayZ0CHHGHnTC%2Fh%2F6SBjqlAT1%2B7KsPj3eCJnbyS5ZfXUoE%2BlV%2BTk8oyT6lRkuzDi5aEGoj3VUhHkiA1q3%2F7RaTCQ0k3z7ZEuLNM7LXgms%2Bt3FaXgu56LvwrJ6L0GK11LRMeyGqQzxITsHmiR%2Fa9OLFoCjEtoaRytEmqhsR6hANFhecBmMexp29SRuVJui6nDb72lgs6fFuBNjDnF7KKVEH8urj%2BGEbO2Djzh32qT%2B4K9hgN6ve2w%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20220420T051654Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5Q3G6HW3%2F20220420%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=b2f773ea90fc01f3865bd17072692250a2fbb7599426fd1d0685c6810bcb9774&amp;hash=f6609fd7e985ba781e0b045298b9cf39e45738796dd701dc3120327365df6cb7&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0891584920316269&amp;tid=spdf-af406ee1-5d31-4263-8bd7-34e05f0209d7&amp;sid=26033829405357478e3a4f10bfaf8bba6257gxrqa&amp;type=client\" target=\"_blank\" rel=\"noopener\">2021\u5e741\u6708 Nicotinamide mononucleotide inhibits hepatic stellate cell activation to prevent liver fibrosis via promoting PGE 2 degradation<\/a><\/span><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-4036-0-1-3\" class=\"so-panel widget widget_sow-editor\" data-index=\"3\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.aging-us.com\/article\/202453\/pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e7412\u6708 Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7648491\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e7412\u6708 NMN\u900f\u904e\u6539\u5584\u7c92\u7dda\u9ad4\u529f\u80fd\u5931\u5e38\uff0c\u6e1b\u4f4e\u611f\u67d3\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\u7684\u6a5f\u6703\u53ca\u56b4\u91cd\u6027<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/paperchase-aging.s3-us-west-1.amazonaws.com\/pdf\/5f770e8f6b11280008528637.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e7411\u6708 NMN\u5728\u52d5\u7269\u5be6\u9a57\u80fd\u9006\u8f49\u86cb\u767d\u8cea\u7a69\u614b\u7684\u55aa\u5931\uff0c\u6e1b\u4f4e\u814e\u81df\u8870\u8001<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/reader.elsevier.com\/reader\/sd\/pii\/S0891584920316269?token=5A06D7AB3EFA879E3429F4292158C5AC9BE3B954DC559B29037C50772E43002C6143FE9B8CD88C54676EAC3E78C6D2C5\" target=\"_blank\" rel=\"noopener\">2020\u5e7411\u6708 NMN\u5728\u52d5\u7269\u80fd\u6210\u70ba\u9810\u9632\u809d\u7e96\u7dad\u5316\u7684\u65b0\u4e00\u4ee3\u6cbb\u7642<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.metabolismjournal.com\/article\/S0026-0495(20)30266-3\/fulltext\" target=\"_blank\" rel=\"noopener\">2020\u5e7410\u6708 NMN\u80fd\u6709\u6548\u589e\u5f37\u7cd6\u5c3f\u52d5\u7269\u89d2\u819c\u4e0a\u76ae\u7834\u640d\u7684\u7652\u5408\u53ca\u795e\u7d93\u5eb7\u5fa9<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7576234\/pdf\/ACEL-19-e13213.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e7410\u6708 NMN\u5728\u52d5\u7269\u5be6\u9a57\u80fd\u9006\u8f49\u5e74\u8001\u5fc3\u81df\u7684\u6536\u7e2e\u529f\u80fd\u969c\u7919<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.cell.com\/cell-reports\/pdfExtended\/S2211-1247(20)30972-4\" target=\"_blank\" rel=\"noopener\">2020\u5e748\u6708 NMN\u80fd\u9006\u8f49\u52d5\u7269\u5fc3\u8840\u7ba1\u5167\u76ae\u7d30\u80de\u529f\u80fd\u5931\u8abf<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S000629522030246X\/pdfft?md5=e6a8b00be95a2850def8b7d4576e4e87&amp;pid=1-s2.0-S000629522030246X-main.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e748\u6708 NMN\u80fd\u9006\u8f49\u52d5\u7269\u7684\u5375\u6bcd\u7d30\u80de\u8870\u8001 \u7406\u8ad6\u4e0a\u80fd\u6539\u5584\u4eba\u985e\u5973\u6027\u4e0d\u80b2<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/acel.13206\" target=\"_blank\" rel=\"noopener\">2020\u5e748\u6708 NMN\u5728\u52d5\u7269\u80fd\u6709\u6548\u6291\u5236\u53ca\u6e1b\u5c11\u5375\u6bcd\u7d30\u80deDNA\u7570\u8b8a \u6709\u671b\u6210\u70ba\u5973\u6027\u4e0d\u80b2\u6cbb\u7642\u65b9\u6848\u4e4b\u4e00\u80b2<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7248519\/pdf\/mmr-22-01-0145.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e747\u6708 NMN\u5728\u52d5\u7269\u80fd\u6cbb\u7642\u670d\u7528\u985e\u56fa\u9187\u6240\u5c0e\u81f4\u7684\u9aa8\u8cea\u758f\u9b06<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923020301453?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2020\u5e747\u6708 NMN\u80fd\u6709\u6548\u6e1b\u4f4e\u52d5\u7269\u56b4\u91cd\u4f4e\u8840\u7cd6\u6240\u5f15\u81f4\u7684\u8166\u7d30\u80de\u53d7\u640d<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S221323172030094X\/pdfft?md5=59e2b5667af59afa2484d1f110579b7a&amp;pid=1-s2.0-S221323172030094X-main.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e747\u6708 NMN\u53ef\u80fd\u5c0d\u4eba\u985e\u8001\u5e74\u6027\u9ec3\u6591\u90e8\u75c5\u8b8a\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11033-020-05590-5.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e746\u6708 \u63a2\u8a0eNMN\u6cbb\u7642\u795e\u7d93\u91ab\u5b78\u75be\u75c5\u7684\u53ef\u80fd\u6027<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7313029\/pdf\/ijms-21-03756.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e745\u6708 NMN\u5c0d\u52d5\u7269\u56e0\u7cd6\u5c3f\u75c5\u8166\u90e8\u5931\u61b6\u53ca\u5931\u667a\u6709\u9810\u9632\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcell.2020.00246\/pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e744\u6708 \u63a2\u8a0eNMN\u5c0d\u5404\u7a2e\u4e0d\u540c\u75be\u75c5\u7684\u6cbb\u7642\u53ef\u884c\u6027<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajpcell.00445.2019?rfr_dat=cr_pub++0pubmed&amp;url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org\" target=\"_blank\" rel=\"noopener\">2020\u5e744\u6708 NMN\u80fd\u6709\u6548\u964d\u4f4eUVB\u7167\u5c04\u5f15\u767c\u7684\u89d2\u819c\u5167\u76ae\u7d30\u80de\u51cb\u4ea1<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7206476\/pdf\/11357_2020_Article_165.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e744\u6708 NMN\u5728\u5e74\u9081\u52d5\u7269\u80fd\u4fc3\u9032\u795e\u7d93\u8840\u7ba1\u518d\u751f<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7226525\/pdf\/cells-09-00791.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e744\u6708 NMN\u5728\u52d5\u7269\u80fd\u6e1b\u8f15\u6bcd\u9ad4\u904e\u91cd\u5f15\u81f4\u7684\u4ee3\u8b1d\u75be\u75c5<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7042676\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2020\u5e743\u6708 NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u9871\u5167\u51fa\u8840\u554f\u984c\u4e26\u4fdd\u8b77\u8166\u7d44\u7e54<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0014488619302912?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2020\u5e743\u6708 NMN\u5728\u52d5\u7269\u80fd\u6cbb\u7642\u6025\u6027\u8166\u640d\u50b7\u548c\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0165032719322438?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2020\u5e742\u6708 NMN\u5728\u52d5\u7269\u80fd\u6709\u6548\u5730\u6cbb\u7642\u6291\u9b31\u75c7<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.cell.com\/cell-reports\/pdfExtended\/S2211-1247(20)30083-8\" target=\"_blank\" rel=\"noopener\">2020\u5e742\u6708 NMN\u53ef\u4f7f\u8870\u8001\u52d5\u7269\u7684\u5375\u6bcd\u7d30\u80de\u8cea\u91cf\u6062\u5fa9\u6d3b\u529b\uff0c\u5f9e\u800c\u5c0e\u81f4\u751f\u80b2\u529b\u6062\u5fa9<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajpcell.00445.2019\" target=\"_blank\" rel=\"noopener\">2020\u5e742\u6708 NMN\u5c0d\u52d5\u7269\u80fd\u6709\u6548\u9632\u6b62\u89d2\u819c\u5167\u76ae\u7d30\u80de\u51cb\u4ea1<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs11357-020-00165-5\" target=\"_blank\" rel=\"noopener\">2020\u5e742\u6708 NMN\u5c0d\u52d5\u7269\u80fd\u6436\u6551\u795e\u7d93\u8840\u7ba1\u529f\u80fd\uff0c\u589e\u52a0\u8166\u8840\u6d41\u91cf\u4e26\u6539\u5584\u8a8d\u77e5\u4efb\u52d9\u7684\u8868\u73fe<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #034179;\"><a style=\"color: #034179;\" href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/HYPERTENSIONAHA.119.13357\" target=\"_blank\" rel=\"noopener\">2020\u5e741\u6708 NMN\u5728\u52d5\u7269\u80fd\u6539\u5584\u56e0\u627f\u53d7\u904e\u5927\u58d3\u529b\u800c\u5f15\u81f4\u7684\u5fc3\u808c\u7d30\u80de\u80a5\u5927<\/a><\/span><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-4036-0-1-4\" class=\"so-panel widget widget_sow-editor\" data-index=\"4\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p style=\"line-height: 15.0pt;\"><strong><span style=\"font-family: \u5fae\u8edf\u6b63\u9ed1\u9ad4, sans-serif; font-size: 12pt;\">\u4ee5\u4e0b\u662f\u6b63\u5728\u9032\u884c\u4e2d\/ \u5df2\u7814\u7a76\u767c\u5831\u6210\u679c\u7684\u4eba\u985e\u81e8\u5e8a\u5be6\u9a57 :\u00a0<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.jstage.jst.go.jp\/article\/endocrj\/advpub\/0\/advpub_EJ19-0313\/_pdf\/-char\/en\" target=\"_blank\" rel=\"noopener\">2019\u5e7411\u6708 NMN\u4eba\u985e\u81e8\u5e8a\u5be6\u9a57\u670d\u7528\u5f8c\u6c92\u6709\u4e0d\u826f\u53cd\u61c9<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6511662\/pdf\/12929_2019_Article_527.pdf\" target=\"_blank\" rel=\"noopener\">2019\u5e745\u6708 \u7e3d\u7d50NMN\u5c0d\u4ee3\u8b1d\u75be\u75c5\u7684\u7642\u6548\u53ca\u8a0e\u8ad6\u5176\u4eba\u985e\u81e8\u5e8a\u5be6\u9a57<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6359187\/pdf\/biomolecules-09-00034.pdf\" target=\"_blank\" rel=\"noopener\">2019\u5e741\u6708 \u63a2\u8a0eNMN\u5c0d\u4fdd\u8b77\u5fc3\u81df,\u9810\u9632\u7cd6\u5c3f,\u9810\u9632\u8a8d\u77e5\u969c\u7919,\u53ca\u80a5\u80d6\u5f15\u8d77\u7684\u4f75\u767c\u75c7\u7b49\u75c5\u75c7\u7684\u6cbb\u7642\u6548\u679c<\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03151239?term=NCT03151239&amp;rank=1\" target=\"_blank\" rel=\"noopener\">2017\u5e747\u6708\u4eba\u985e\u670d\u7528NMN\u5c0d\u5fc3\u8840\u7ba1\u53ca\u4ee3\u8b1d\u75c7\u7684\u5f71\u97ff <\/a><\/span><\/p>\n<p><span style=\"font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5515004\/pdf\/npjamd201621.pdf\" target=\"_blank\" rel=\"noopener\">2016\u5e743\u6708\u65e5\u672c\u6176\u61c9\u7fa9\u587e\u5927\u5b66\u806f\u540c\u7f8e\u570b\u8056\u8def\u6613\u65af\u83ef\u76db\u9813\u5927\u5b78\u958b\u59cb\u4e86\u7b2c\u4e00\u671f\u95dc\u65bcNMN\u4eba\u985e\u81e8\u5e8a\u5be6\u9a57<\/a><\/span><\/p>\n<p style=\"line-height: 15.0pt;\"><span style=\"font-family: \u5fae\u8edf\u6b63\u9ed1\u9ad4, sans-serif; font-size: 12pt;\">\u5168\u7403\u5404\u5730\u5df2\u6709\u4e0d\u5c11\u91ab\u751f\u53ca\u79d1\u5b78\u5bb6\u6b63\u958b\u59cb\u5c0d NMN \u9032\u884c\u4eba\u985e\u81e8\u5e8a\u7814\u7a76\u3002\u5f9e\u591a\u6b21\u5df2\u77e5\u7684\u52d5\u7269\u81e8\u5e8a\u6548\u679c\u5206\u6790\uff0c\u79d1\u5b78\u5bb6\u90fd\u8a8d\u70ba NMN \u5c0d\u65bc\u4eba\u985e\u7dad\u8b77\u5065\u5eb7\u3001\u5c0d\u6297\u8870\u8001\u7684\u6210\u6548\u662f\u6a02\u89c0\u548c\u6b63\u9762\u7684\u3002\u76f8\u4fe1\u4eba\u985e\u81e8\u5e8a\u7d50\u679c\u9762\u4e16\u7684\u6642\u9593\u5df2\u4e0d\u9060\u77e3\u3002<\/span><\/p>\n<p style=\"line-height: 15.0pt;\"><span style=\"font-family: \u5fae\u8edf\u6b63\u9ed1\u9ad4, sans-serif; font-size: 12pt;\">\u7b46\u8005\u662f\u8a3b\u518a\u91ab\u751f\uff0cNMN\u5c0d\u4eba\u985e\u5065\u5eb7\u7684\u5e6b\u52a9\u548c\u5ef6\u9072\u4eba\u985e\u8870\u8001\u7684\u6210\u6548 \u6211\u6df1\u4fe1\u4e0d\u7591\u3002\u6211\u548c\u5bb6\u4eba\u6bcf\u5929\u670d\u7528NMN\u5df2\u6709\u76f8\u7576\u7684\u6642\u9593\u3002\u6211\u4e5f\u5efa\u8b70\u5927\u5bb6\u4eca\u5929\u8d77\u958b\u59cb\u670d\u7528\u3002<\/span><\/p>\n<\/div>\n<\/div><\/div><div id=\"panel-4036-0-1-5\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"5\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6477631\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2019\u5e745\u6708NMN\u5c0d\u52d5\u7269\u8166\u8840\u7ba1\u75be\u75c5\u6709\u5e6b\u52a9\u4e26\u80fd\u6539\u5584\u8166\u529b<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6472410\/pdf\/41419_2019_Article_1569.pdf\" target=\"_blank\" rel=\"noopener\">2019\u5e744\u6708NMN\u5c0d\u52d5\u7269\u589e\u9032\u9593\u5145\u8cea\u5e79\u7d30\u80de\u5c0d\u9aa8\u8cea\u589e\u751f\u7684\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.physiology.org\/doi\/abs\/10.1152\/ajpheart.00039.2019\" target=\"_blank\" rel=\"noopener\">2019\u5e743\u6708\u5efa\u8b70NMN\u61c9\u88ab\u5217\u70ba\u6cbb\u7642\u4eba\u985e\u5fc3\u8840\u7ba1\u75c5\u8001\u5316\u7684\u56b4\u8b39\u65b9\u6848\u4e4b\u4e00<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1043661818304791\" target=\"_blank\" rel=\"noopener\">2019\u5e743\u6708NMN\u53ef\u80fd\u5c0d\u52d5\u7269\u6216\u4eba\u985e\u9aa8\u8cea\u758f\u9b06\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007%2Fs10157-019-01719-4.pdf\" target=\"_blank\" rel=\"noopener\">2019\u5e743\u6708NMN\u53ef\u80fd\u662f\u52d5\u7269\u7cd6\u5c3f\u814e\u75c5\u672a\u4f86\u6709\u6548\u7684\u6cbb\u7642<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs10522-019-09805-6\" target=\"_blank\" rel=\"noopener\">2019\u5e743\u6708\u63a2\u8a0eNMN\u5c0d\u6297\u8870\u8001\u53ca\u7f3a\u8840\u72c0\u6cc1\u6cbb\u7642\u7684\u539f\u7406<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6395802\/pdf\/41598_2019_Article_39419.pdf\" target=\"_blank\" rel=\"noopener\">2019\u5e742\u6708NMN\u5c0d\u52d5\u7269\u7dda\u7c92\u9ad4\u75be\u75c5\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs11064-019-02729-0\" target=\"_blank\" rel=\"noopener\">2019\u5e741\u6708NMN\u6975\u6709\u6f5b\u529b\u91ab\u6cbb\u795e\u7d93\u9000\u5316\u6027\u75be\u75c5<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6224504\/pdf\/41514_2018_Article_29.pdf\" target=\"_blank\" rel=\"noopener\">2018\u5e7411\u6708NMN\u5c0d\u52d5\u7269\u8166\u90e8\u589e\u52a0\u8a8d\u77e5\u80fd\u529b<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0041008X18304642?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2018\u5e7410\u6708NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u92c1\u8cea\u5c0e\u81f4\u7684\u9aa8\u8cea\u758f\u9b06\u75c5<\/a><\/span><\/p>\n<p style=\"tab-stops: 45.8pt 91.6pt 137.4pt 183.2pt 229.0pt 274.8pt 320.6pt 366.4pt 412.2pt 458.0pt 503.8pt 549.6pt 595.4pt 641.2pt 687.0pt 732.8pt; background: white;\"><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6139007\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2018\u5e7410\u6708NMN\u5728\u52d5\u7269\u80fd\u6709\u6548\u4fdd\u8b77\u690e\u9593\u76e4\u7684\u9000\u5316<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6171817\/pdf\/jciinsight-3-120182.pdf\" target=\"_blank\" rel=\"noopener\">2018\u5e749\u6708NMN\u5927\u5927\u589e\u52a0\u4e86\u52d5\u7269\u5728<span style=\"background: white;\">\u5931\u8840\u6027\u4f11\u514b<\/span><span style=\"background: white;\">\u7684\u5b58\u6d3b\u6a5f\u6703<\/span><\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.jmmc-online.com\/article\/S0022-2828(18)30361-4\/fulltext\" target=\"_blank\" rel=\"noopener\">2018\u5e748\u6708NMN\u5c0d\u52d5\u7269\u6709\u4fdd\u8b77\u5fc3\u81df\u7684\u4f5c\u7528<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6046249\/pdf\/aging-10-101469.pdf\" target=\"_blank\" rel=\"noopener\">2018\u5e746\u6708NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u8996\u7db2\u819c\u8868\u76ae\u7d44\u7e54\u8001\u5316<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #339966;\"><a style=\"color: #339966;\" href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(18)30152-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867418301521%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener\">2018\u5e743\u6708NMN\u80fd\u6709\u6548\u5c0d\u52d5\u7269\u589e\u52a0\u5404\u8655\u5668\u5b98\u7684\u8840\u6d41\u91cf<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"http:\/\/journals.lww.com\/co-psychiatry\/Abstract\/publishahead\/Nicotinamide_adenine_dinucleotide_and_its_related.99307.aspx\" target=\"_blank\" rel=\"noopener\">2017\u5e7412\u6708NMN\/Nicotinamide Riboside\u53ef\u80fd\u5c0d\u4eba\u985e\u8a8d\u77e5\u969c\u7919\u75c7(\u4fd7\u7a31\u8001\u4eba\u75f4\u5446)\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/www.nature.com\/articles\/s41598-017-14866-z.pdf\" target=\"_blank\" rel=\"noopener\">2017\u5e7411\u6708NMN\u5c0d\u52d5\u7269\u8461\u8404\u7cd6\u8010\u53d7\u4e0d\u826f\u53ca\u6e1b\u8102\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5658765\/pdf\/etm-14-05-4181.pdf\" target=\"_blank\" rel=\"noopener\">2017\u5e7411\u6708NMN\u5c0d\u52d5\u7269\u7cd6\u5c3f\u75c5\u814e\u75c5\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"http:\/\/www.jmmc-online.com\/article\/S0022-2828(17)30303-6\/abstract\" target=\"_blank\" rel=\"noopener\">2017\u5e7411\u6708NMN\u5c0d\u52d5\u7269\u5fc3\u81df\u8870\u7aed\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bph.13979\/epdf\" target=\"_blank\" rel=\"noopener\">2017\u5e7411\u6708NMN\u80fd\u6709\u6548\u6e1b\u4f4e\u5c0d\u52d5\u7269\u8166\u8840\u7ba1\u6813\u585e\u6cbb\u7642\u6240\u5f15\u8d77\u7684\u4f75\u767c\u75c7<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5518663\/pdf\/main.pdf\" target=\"_blank\" rel=\"noopener\">2017\u5e748\u6708NMN\/Nicotinamide Riboside\u80fd\u6709\u6548\u6e1b\u4f4e\u5c0d\u52d5\u7269\u808c\u8089\u65b0\u9673\u4ee3\u8b1d\u5f15\u81f4\u7684\u8870\u8001<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"http:\/\/jasn.asnjournals.org\/content\/28\/8\/2337.abstract\" target=\"_blank\" rel=\"noopener\">2017\u5e748\u6708NMN\u80fd\u6709\u6548\u4fdd\u8b77\u52d5\u7269\u514d\u53d7\u6025\u6027\u814e\u640d\u50b7\u7684\u50b7\u5bb3<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5657423\/pdf\/sigtrans201717.pdf\" target=\"_blank\" rel=\"noopener\">2017\u5e747\u6708NMN\u5c0d\u52d5\u7269\u5927\u8178\u9000\u5316\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/insight.jci.org\/articles\/view\/93885\/pdf\" target=\"_blank\" rel=\"noopener\">2017\u5e747\u6708NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u5fc3\u808c\u75c7\u7684\u5fc3\u81df\u529f\u80fd<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"https:\/\/www.nature.com\/articles\/s41598-017-00851-z.pdf\" target=\"_blank\" rel=\"noopener\">2017\u5e744\u6708NMN\u80fd\u6709\u6548\u6e1b\u4f4e\u5c0d\u52d5\u7269\u51fa\u8840\u6027\u4e2d\u98a8\u7684\u8166\u6c34\u816b\u548c\u8166\u7d30\u80de\u6b7b\u4ea1<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S030439401730246X?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2017\u5e744\u6708NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u8a8d\u77e5\u969c\u7919\u75c7(\u4fd7\u7a31\u8001\u4eba\u75f4\u5446)\u7684\u5404\u7a2e\u75c5\u7406\u5f71\u97ff<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #666699;\"><a style=\"color: #666699;\" href=\"http:\/\/journal.nichigan.or.jp\/Disp?style=abst&amp;vol=121&amp;year=2017&amp;mag=0&amp;number=3&amp;start=232\" target=\"_blank\" rel=\"noopener\">2017\u5e743\u6708NMN\u80fd\u6709\u6548\u5728\u52d5\u7269\u4fdd\u8b77\u8996\u7db2\u819c\u75c5\u8b8a<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #008080;\"><a style=\"color: #008080;\" href=\"http:\/\/www.cell.com\/cell-metabolism\/pdf\/S1550-4131(16)30495-8.pdf\" target=\"_blank\" rel=\"noopener\">2016\u5e7412\u6708NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u5e74\u8001\u6642\u7684\u9ad4\u80fd\uff0c\u65b0\u9673\u4ee3\u8b1d\u53ca\u8996\u529b\uff0c\u4e26\u80fd\u6e1b\u4f4e\u9ad4\u91cd\uff0c\u8840\u8102\u53ca\u7cd6\u5c3f\u75c5<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #008080;\"><a style=\"color: #008080;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5580241\/pdf\/nihms900541.pdf\" target=\"_blank\" rel=\"noopener\">2016\u5e7411\u6708NMN\u80fd\u5f37\u70c8\u4fdd\u8b77\u52d5\u7269\u7684\u5c40\u90e8\u6027\u8166\u7f3a\u8840\u5e36\u4f86\u7684\u50b7\u5bb3<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #008080;\"><a style=\"color: #008080;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4990541\/pdf\/fphar-07-00258.pdf\" target=\"_blank\" rel=\"noopener\">2016\u5e748\u6708NMN\u80fd\u6709\u6548\u6539\u5584\u80a5\u80d6\u52d5\u7269\u7684\u5404\u7a2e\u4ee3\u8b1d\u6307\u6a19\uff0c\u6548\u679c\u53ef\u6bd4\u7f8e\u505a\u904b\u52d5<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #008080;\"><a style=\"color: #008080;\" href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006899316303018?via%3Dihub\" target=\"_blank\" rel=\"noopener\">2016\u5e747\u6708NMN\u5c0d\u52d5\u7269\u8a8d\u77e5\u969c\u7919(\u8001\u4eba\u7661\u5446)\u6709\u826f\u597d\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #008080;\"><a style=\"color: #008080;\" href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.12461\/pdf\" target=\"_blank\" rel=\"noopener\">2016\u5e746\u6708NMN\u80fd\u9006\u8f49\u52d5\u7269\u8840\u7ba1\u8001\u5316<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #808000;\"><a style=\"color: #808000;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4113526\/pdf\/etm-08-03-0943.pdf\" target=\"_blank\" rel=\"noopener\">2014\u5e747\u6708NMN\u5c0d\u52d5\u7269\u67cf\u91d1\u905c\u75c5\u6709\u7642\u6548<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #808000;\"><a style=\"color: #808000;\" href=\"http:\/\/journals.plos.org\/plosone\/article\/file?id=10.1371\/journal.pone.0098972&amp;type=printable\" target=\"_blank\" rel=\"noopener\">2014\u5e746\u6708NMN\u5c0d\u52d5\u7269\u5fc3\u81df\u7f3a\u8840\u6709\u4fdd\u8b77\u4f5c\u7528<\/a><\/span><\/p>\n<p><span style=\"font-family: 'Microsoft JhengHei', sans-serif; font-size: 12pt; color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.cell.com\/action\/showPdf?pii=S1550-4131%2811%2900346-9\" target=\"_blank\" rel=\"noopener\">2011\u5e7410\u6708 NMN\u80fd\u6709\u6548\u6539\u5584\u52d5\u7269\u56e0\u5e74\u8001\u6216\u98f2\u98df\u8a98\u767c\u7684\u4e8c\u578b\u7cd6\u5c3f<\/a><\/span><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-4036-0-2\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u6709\u95dcNMN\u7684\u4eba\u985e\/\u53ca\u52d5\u7269\u4e4b\u81e8\u5e8a\u5be6\u9a57 2023\u5e743\u6708 Nicotinamide Mononucleotide Attenuates LPS-Induced Acute Lung Injury With Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects 2023\u5e743\u6708 The cardioprotective role of sirtuins is mediated in part by regulating KATP channel surface expression 2023\u5e743\u6708 Gut microbiota-derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling 2023\u5e742\u6708 The additive effects of nicotinamide mononucleotide and melatonin on mitochondrial [&hellip;]\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4036","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/pages\/4036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/comments?post=4036"}],"version-history":[{"count":18,"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/pages\/4036\/revisions"}],"predecessor-version":[{"id":5455,"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/pages\/4036\/revisions\/5455"}],"wp:attachment":[{"href":"https:\/\/www.antiaging.com.hk\/en\/wp-json\/wp\/v2\/media?parent=4036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}